P-Cadherin anticorps (AA 24-350)

N° du produit ABIN7269142

Cet anticorps Lapin Polyclonal détecte spécifiquement P-Cadherin dans WB, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour P-Cadherin anticorps (AA 24-350) (ABIN7269142)

Antigène: P-Cadherin (CDH3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P-Cadherin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-P-Cadherin anticorps

Épitope: AA 24-350

Fonction: CDH3 Rabbit pAb

Séquence: SEPCRAVFRE AEVTLEAGGA EQEPGQALGK VFMGCPGQEP ALFSTDNDDF TVRNGETVQE RRSLKERNPL KIFPSKRILR RHKRDWVVAP ISVPENGKGP FPQRLNQLKS NKDRDTKIFY SITGPGADSP PEGVFAVEKE TGWLLLNKPL DREEIAKYEL FGHAVSENGA SVEDPMNISI IVTDQNDHKP KFTQDTFRGS VLEGVLPGTS VMQVTATDED DAIYTYNGVV AYSIHSQEPK DPHDLMFTIH RSTGTISVIS SGLDREKVPE YTLTIQATDM DGDGSTTTAV AVVEILDAND NAPMFDPQKY EAHVPENAVG HEVQRLT

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 24-350 of human CDH3 (NP_001784.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur P-Cadherin

Antigène: P-Cadherin (CDH3)

Autre désignation: CDH3

Sujet: This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS).,CDH3,CDHP,HJMD,PCAD,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cadherins,Tight Junctions,Cytoskeleton,Wnt/β-Catenin Signaling Pathway,Neuroscience,CDH3

Poids moléculaire: 86kDa/91kDa

ID gène: 1001

UniProt: P22223