PHOX2B anticorps
Aperçu rapide pour PHOX2B anticorps (ABIN7269159)
Antigène
Voir toutes PHOX2B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Fonction
- PHOX2B Rabbit mAb
-
Réactivité croisée
- Humain, Souris
-
Attributs du produit
- Monoclonal Antibodies
-
Purification
- Affinity purification
-
Immunogène
- A synthesized peptide derived from human PHOX2B
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB,1:500 - 1:2000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- PHOX2B (Paired-Like Homeobox 2b (PHOX2B))
-
Autre désignation
- PHOX2B
-
Sujet
- The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome. [provided by RefSeq, Jul 2016],NBLST2, NBPhox, PMX2B,Epigenetics & Nuclear Signaling,Neuroscience,Signal Transduction,Transcription Factors,PHOX2B
-
Poids moléculaire
- 35kDa
-
ID gène
- 8929
-
UniProt
- Q99453
Antigène
-