PAK4/PAK5/PAK6 (pSer474), (pSer560), (pSer602) anticorps

N° du produit ABIN7269163

Cet anticorps Lapin Monoclonal détecte spécifiquement PAK4/PAK5/PAK6 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour PAK4/PAK5/PAK6 (pSer474), (pSer560), (pSer602) anticorps (ABIN7269163)

Antigène: PAK4/PAK5/PAK6

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB)

Détail du produit

Épitope: pSer474, pSer560, pSer602

Fonction: Phospho-PAK4/PAK5/PAK6-S474/S560/S602 Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Phosphorylated Antibodies

Purification: Affinity purification

Immunogène: A phospho specific peptide corresponding to residues surrounding S474 of human PAK4

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détail du antigène

Antigène: PAK4/PAK5/PAK6

Sujet: PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],PAK4/PAK5/PAK6

Poids moléculaire: 64, 80, 75 kDa

ID gène: 10298, 57144, 56924