PYM anticorps
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- Antigène Voir toutes PYM (WIBG) Anticorps
- PYM (WIBG) (Partner of Y14 and mago (WIBG))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PYM est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Fonction
- PYM1 Rabbit pAb
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human PYM1.
- Isotype
- IgG
- Top Product
- Discover our top product WIBG Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- PYM (WIBG) (Partner of Y14 and mago (WIBG))
- Autre désignation
- PYM1 (WIBG Produits)
- Synonymes
- anticorps BEST:HL05757, anticorps CG10330, anticorps CG30176, anticorps Dmel\\CG30176, anticorps PYM, anticorps Pym, anticorps UD3, anticorps A030010B05Rik, anticorps zgc:65891, anticorps zgc:77281, anticorps Partner of Y14 and Mago, anticorps Wibg protein, anticorps PYM homolog 1, exon junction complex associated factor L homeolog, anticorps PYM homolog 1, exon junction complex associated factor, anticorps Pym, anticorps wibg, anticorps pym1.L, anticorps PYM1, anticorps Pym1, anticorps pym1
- Sujet
- Key regulator of the exon junction complex (EJC, a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD or translation. Acts as an EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. Interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions. May bind RNA, the relevance of RNA-binding remains unclear in vivo, RNA-binding was detected by PubMed:14968132, while PubMed:19410547 did not detect RNA-binding activity independently of the EJC.,PYM, WIBG,Epigenetics & Nuclear Signaling,PYM1
- ID gène
- 84305
- UniProt
- Q9BRP8
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