PDE11A anticorps (AA 712-933)

N° du produit ABIN7269298

Cet anticorps Lapin Polyclonal détecte spécifiquement PDE11A dans WB et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour PDE11A anticorps (AA 712-933) (ABIN7269298)

Antigène: PDE11A (phosphodiesterase 11A (PDE11A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE11A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-PDE11A anticorps

Épitope: AA 712-933

Fonction: PDE11A Rabbit pAb

Séquence: NNAFQAKSGS ALAQLYGTSA TLEHHHFNHA VMILQSEGHN IFANLSSKEY SDLMQLLKQS ILATDLTLYF ERRTEFFELV SKGEYDWNIK NHRDIFRSML MTACDLGAVT KPWEISRQVA ELVTSEFFEQ GDRERLELKL TPSAIFDRNR KDELPRLQLE WIDSICMPLY QALVKVNVKL KPMLDSVATN RSKWEELHQK RLLASTASSS PASVMVAKED RN

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 712-933 of human PDE11A (NP_058649.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PDE11A

Antigène: PDE11A (phosphodiesterase 11A (PDE11A))

Autre désignation: PDE11A

Sujet: The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.,PDE11A;PPNAD2,PDE11A

Poids moléculaire: 55kDa/65kDa/78kDa/104kDa

ID gène: 50940

UniProt: Q9HCR9

Pathways: cAMP Metabolic Process