PDE12 anticorps (AA 17-300)

N° du produit ABIN7269299

Détail du produit anti-PDE12 anticorps

Antigène: PDE12 (Phosphodiesterase 12 (PDE12))

Épitope: AA 17-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE12 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Fonction: PDE12 Rabbit pAb

Séquence: AVEKLSRAEA GSQTAAGAME RAVVRCVPSE PKLSLSFALA DGSHKNMQRD QSEPLGRVLS RIATNALKGH AKAAAAKKSR KSRPNASGGA ACSGPGPEPA VFCEPVVKLY YREEAVAEDV LNVDAWQDGA VLQIGDVKYK VERNPPAFTE LQLPRYIMAG FPVCPKLSLE FGDPASSLFR WYKEAKPGAA EPEVGVPSSL SPSSPSSSWT ETDVEERVYT PSNADIGLRL KLHCTPGDGQ RFGHSRELES VCVVEAGPGT CTFDHRHLYT KKVTEDALIR TVSY

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 17-300 of human PDE12 (NP_001309106.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PDE12

Antigène: PDE12 (Phosphodiesterase 12 (PDE12))

Autre désignation: PDE12 (PDE12 Produits)

Synonymes: anticorps 2'-PDE, anticorps E430028B21Rik, anticorps LRRGT00074, anticorps RGD1310975, anticorps phosphodiesterase 12 S homeolog, anticorps phosphodiesterase 12, anticorps pde12.S, anticorps PDE12, anticorps pde12, anticorps Pde12

Sujet: Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. Degrades triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs. Suppression of this enzyme increases cellular 2-5A levels and decreases viral replication in cultured small-airway epithelial cells and Hela cells.,PDE12,2-PDE,PDE12

ID gène: 201626

UniProt: Q6L8Q7