PDE3A anticorps (AA 380-660)

N° du produit ABIN7269301

Cet anticorps Lapin Polyclonal détecte spécifiquement PDE3A dans WB, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour PDE3A anticorps (AA 380-660) (ABIN7269301)

Antigène: PDE3A (phosphodiesterase 3A, cGMP-Inhibited (PDE3A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE3A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-PDE3A anticorps

Épitope: AA 380-660

Fonction: PDE3A Rabbit pAb

Séquence: LLSTQLTFQA IHKPRVNPVT SLSENYTCSD SEESSEKDKL AIPKRLRRSL PPGLLRRVSS TWTTTTSATG LPTLEPAPVR RDRSTSIKLQ EAPSSSPDSW NNPVMMTLTK SRSFTSSYAI SAANHVKAKK QSRPGALAKI SPLSSPCSSP LQGTPASSLV SKISAVQFPE SADTTAKQSL GSHRALTYTQ SAPDLSPQIL TPPVICSSCG RPYSQGNPAD EPLERSGVAT RTPSRTDDTA QVTSDYETNN NSDSSDIVQN EDETECLREP LRKASACSTY A

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 380-660 of human PDE3A (NP_000912.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PDE3A

Antigène: PDE3A (phosphodiesterase 3A, cGMP-Inhibited (PDE3A))

Autre désignation: PDE3A

Sujet: This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,HTNB,CGI-PDE,CGI-PDE A,CGI-PDE-A,PDE3A,Signal Transduction,PDE3A

Poids moléculaire: 125kDa

ID gène: 5139

UniProt: Q14432

Pathways: cAMP Metabolic Process