PLSCR1 anticorps

N° du produit ABIN7269354

Cet anticorps anti-PLSCR1 Monoclonal Lapin (ABIN7269354) détecte spécifiquement PLSCR1 dans WB, IHC et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PLSCR1 anticorps (ABIN7269354)

Antigène: PLSCR1 (phospholipid Scramblase 1 (PLSCR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PLSCR1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-PLSCR1 anticorps

Fonction: Phospholipid Scramblase 1 (PLSCR1) Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human Phospholipid Phospholipid Scramblase 1 (PLSCR1) (PLSCR1)

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PLSCR1

Antigène: PLSCR1 (phospholipid Scramblase 1 (PLSCR1))

Autre désignation: PLSCR1

Sujet: Catalyzes calcium-induced ATP-independent rapid bidirectional and non-specific movement of phospholipids (lipid scrambling or lipid flip-flop between the inner and outer leaflet of the plasma membrane resulting in collapse of the phospholipid asymmetry which leads to phosphatidylserine externalization on the cell surface. Mediates calcium-dependent phosphatidylserine externalization and apoptosis in neurons via its association with TRPC5 (By similarity. Also exhibits magnesium-dependent nuclease activity against double-stranded DNA and RNA but not single-stranded DNA and can enhance DNA decatenation mediated by TOP2A. Negatively regulates FcR-mediated phagocytosis in differentiated macrophages. May contribute to cytokine-regulated cell proliferation and differentiation (By similarity. May play a role in the antiviral response of interferon (IFN by amplifying and enhancing the IFN response through increased expression of select subset of potent antiviral genes. Acts as an attachment receptor for HCV.,MMTRA1B,Calcium Signaling,Cardiovascular,Lipids,Lipids_Lipoproteins/Apolipoproteins,Neuroscience,Signal Transduction,PLSCR1

Poids moléculaire: 35kDa

ID gène: 5359

UniProt: O15162

Pathways: Cellular Response to Molecule of Bacterial Origin