PRDM9 anticorps

N° du produit ABIN7269501

Cet anticorps anti-PRDM9 est un anticorps Lapin Polyclonal détectant PRDM9 dans WB. Adapté pour Humain.

Aperçu rapide pour PRDM9 anticorps (ABIN7269501)

Antigène: PRDM9 (PR Domain Containing 9 (PRDM9))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRDM9 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PRDM9 anticorps

Fonction: PRDM9 Rabbit pAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant protein of human PRDM9.

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PRDM9

Antigène: PRDM9 (PR Domain Containing 9 (PRDM9))

Autre désignation: PRDM9

Sujet: The protein encoded by this gene is a zinc finger protein with histone methyltransferase activity that catalyzes histone H3 lysine 4 trimethylation (H3K4me3) during meiotic prophase. This protein contains multiple domains, including a Kruppel-associated box (KRAB) domain, an SSX repression domain (SSXRD), a PRD1-BF1 and RIZ homologous region, a subclass of SET (PR/SET) domain, and a tandem array of C2H2 zinc fingers. The zinc finger array recognizes a short sequence motif, leading to local H3K4me3, and meiotic recombination hotspot activity. The observed allelic variation alters the DNA-binding sequence specificity of the protein, resulting in distinct meiotic recombination hotspots amongst individuals and populations. Multiple alternate alleles of this gene have been described.,PFM6, KMT8B, MSBP3, ZNF899, MEISETZ,PRDM9

Poids moléculaire: 103kDa

ID gène: 56979

UniProt: Q9NQV7