PRAME anticorps (AA 1-200)

N° du produit ABIN7269507

Cet anticorps anti-PRAME est un anticorps Lapin Polyclonal détectant PRAME dans WB. Adapté pour Humain.

Aperçu rapide pour PRAME anticorps (AA 1-200) (ABIN7269507)

Antigène: PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRAME est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PRAME anticorps

Épitope: AA 1-200

Fonction: PRAME Rabbit pAb

Séquence: MERRRLWGSI QSRYISMSVW TSPRRLVELA GQSLLKDEAL AIAALELLPR ELFPPLFMAA FDGRHSQTLK AMVQAWPFTC LPLGVLMKGQ HLHLETFKAV LDGLDVLLAQ EVRPRRWKLQ VLDLRKNSHQ DFWTVWSGNR ASLYSFPEPE AAQPMTKKRK VDGLSTEAEQ PFIPVEVLVD LFLKEGACDE LFSYLIEKVK

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PRAME (NP_006106.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PRAME

Antigène: PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))

Autre désignation: PRAME

Sujet: This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.,PRAME,CT130,MAPE,OIP-4,OIP4,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cancer,Tumor biomarkers,PRAME

Poids moléculaire: 57kDa

ID gène: 23532

UniProt: P78395

Pathways: Retinoic Acid Receptor Signaling Pathway, Nuclear Hormone Receptor Binding