PRR5 anticorps (AA 109-388)

N° du produit ABIN7269555

Détail du produit anti-PRR5 anticorps

Antigène: PRR5 (Proline Rich 5 (Renal) (PRR5))

Épitope: AA 109-388

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRR5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Fonction: PRR5 Rabbit pAb

Séquence: QKLLDSLAET WDFFFSDVLP MLQAIFYPVQ GKEPSVRQLA LLHFRNAITL SVKLEDALAR AHARVPPAIV QMLLVLQGVH ESRGVTEDYL RLETLVQKVV SPYLGTYGLH SSEGPFTHSC ILEKRLLRRS RSGDVLAKNP VVRSKSYNTP LLNPVQEHEA EGAAAGGTSI RRHSVSEMTS CPEPQGFSDP PGQGPTGTFR SSPAPHSGPC PSRLYPTTQP PEQGLDPTRS SLPRSSPENL VDQILESVDS DSEGIFIDFG RGRGSGMSDL EGSGGRQSVV

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 109-388 of human PRR5 (NP_851850.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PRR5

Antigène: PRR5 (Proline Rich 5 (Renal) (PRR5))

Autre désignation: PRR5 (PRR5 Produits)

Synonymes: anticorps AU043908, anticorps Arhgap8, anticorps C030017C09Rik, anticorps C78947, anticorps Protor-1, anticorps Protor1, anticorps FLJ20185k, anticorps PP610, anticorps PROTOR-1, anticorps PROTOR1, anticorps pp610, anticorps protor1, anticorps protor2, anticorps proline rich 5 (renal), anticorps proline rich 5, anticorps proline rich 5 L homeolog, anticorps Prr5, anticorps PRR5, anticorps prr5.L

Sujet: This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.,PRR5,FLJ20185k,PP610,PROTOR-1,PROTOR1,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Tumor suppressors,Signal Transduction,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,PRR5

Poids moléculaire: 31kDa/32kDa/41kDa/42kDa/45kDa

ID gène: 55615

UniProt: P85299

Pathways: Signalisation PI3K-Akt