PNRC2 anticorps (AA 1-100)

N° du produit ABIN7269556

Cet anticorps Lapin Polyclonal détecte spécifiquement PNRC2 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour PNRC2 anticorps (AA 1-100) (ABIN7269556)

Antigène: PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PNRC2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PNRC2 anticorps

Épitope: AA 1-100

Fonction: PNRC2 Rabbit pAb

Séquence: MGGGERYNIP APQSRNVSKN QQQLNRQKTK EQNSQMKIVH KKKERGHGYN SSAAAWQAMQ NGGKNKNFPN NQSWNSSLSG PRLLFKSQAN QNYAGAKFSE

Réactivité croisée: Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PNRC2 (NP_060231.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PNRC2

Antigène: PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))

Autre désignation: PNRC2

Sujet: Involved in nonsense-mediated mRNA decay (NMD by acting as a bridge between the mRNA decapping complex and the NMD machinery. May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. Required for UPF1/RENT1 localization to the P-body. Plays a role in glucocorticoid receptor-mediated mRNA degradation by interacting with the glucocorticoid receptor NR3C1 in a ligand-dependent manner when it is bound to the 5' UTR of target mRNAs and recruiting the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay. Also acts as a nuclear receptor coactivator. May play a role in controlling the energy balance between energy storage and energy expenditure (By similarity.,PNRC2,PNRC2

Poids moléculaire: 13kDa/15kDa

ID gène: 55629

UniProt: Q9NPJ4