RSAD2 anticorps (AA 42-361)

N° du produit ABIN7269832

Cet anticorps Lapin Polyclonal détecte spécifiquement RSAD2 dans WB et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour RSAD2 anticorps (AA 42-361) (ABIN7269832)

Antigène: RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RSAD2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-RSAD2 anticorps

Épitope: AA 42-361

Fonction: RSAD2 Rabbit pAb

Séquence: LATKRRKQQL VLRGPDETKE EEEDPPLPTT PTSVNYHFTR QCNYKCGFCF HTAKTSFVLP LEEAKRGLLL LKEAGMEKIN FSGGEPFLQD RGEYLGKLVR FCKVELRLPS VSIVSNGSLI RERWFQNYGE YLDILAISCD SFDEEVNVLI GRGQGKKNHV ENLQKLRRWC RDYRVAFKIN SVINRFNVEE DMTEQIKALN PVRWKVFQCL LIEGENCGED ALREAERFVI GDEEFERFLE RHKEVSCLVP ESNQKMKDSY LILDEYMRFL NCRKGRKDPS KSILDVGVEE AIKFSGFDEK MFLKRGGKYI WSKADLKLDW

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 42-361 of human RSAD2 (NP_542388.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RSAD2

Antigène: RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))

Autre désignation: RSAD2

Sujet: Interferon-inducible antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Catalyzes the conversion of cytidine triphosphate (CTP to 3'-deoxy-3',4'-didehydro-CTP (ddhCTP via a SAM-dependent radical mechanism. In turn, ddhCTP acts as a chain terminator for the RNA-dependent RNA polymerases from multiple viruses and directly inhibits viral replication. Therefore, inhibits a wide range of DNA and RNA viruses, including human cytomegalovirus (HCMV, hepatitis C virus (HCV, west Nile virus (WNV, dengue virus, sindbis virus, influenza A virus, sendai virus, vesicular stomatitis virus (VSV, zika virus, and human immunodeficiency virus (HIV-1. Promotes also TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs by facilitating 'Lys-63'-linked ubiquitination of IRAK1 by TRAF6. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor (TCR-mediated GATA3 activation and optimal T-helper 2 (Th2 cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins.,RSAD2,2510004L01Rik,cig33,cig5,vig1,Immunology & Inflammation,RSAD2

Poids moléculaire: 42kDa

ID gène: 91543

UniProt: Q8WXG1

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response