RSAD2 anticorps (AA 42-361)
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- Antigène Voir toutes RSAD2 Anticorps
- RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))
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Épitope
- AA 42-361
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RSAD2 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Fonction
- RSAD2 Rabbit pAb
- Séquence
- LATKRRKQQL VLRGPDETKE EEEDPPLPTT PTSVNYHFTR QCNYKCGFCF HTAKTSFVLP LEEAKRGLLL LKEAGMEKIN FSGGEPFLQD RGEYLGKLVR FCKVELRLPS VSIVSNGSLI RERWFQNYGE YLDILAISCD SFDEEVNVLI GRGQGKKNHV ENLQKLRRWC RDYRVAFKIN SVINRFNVEE DMTEQIKALN PVRWKVFQCL LIEGENCGED ALREAERFVI GDEEFERFLE RHKEVSCLVP ESNQKMKDSY LILDEYMRFL NCRKGRKDPS KSILDVGVEE AIKFSGFDEK MFLKRGGKYI WSKADLKLDW
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 42-361 of human RSAD2 (NP_542388.2).
- Isotype
- IgG
- Top Product
- Discover our top product RSAD2 Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))
- Autre désignation
- RSAD2 (RSAD2 Produits)
- Synonymes
- anticorps CIG6, anticorps RSAD2, anticorps 2510004L01Rik, anticorps cig33, anticorps cig5, anticorps vig1, anticorps Vig1, anticorps Best5, anticorps si:ch211-276e8.2, anticorps zgc:112342, anticorps viperin, anticorps rsad2, anticorps radical S-adenosyl methionine domain containing 2, anticorps viperin, anticorps RSAD2, anticorps Rsad2, anticorps rsad2, anticorps vig1
- Sujet
- Interferon-inducible antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Catalyzes the conversion of cytidine triphosphate (CTP to 3'-deoxy-3',4'-didehydro-CTP (ddhCTP via a SAM-dependent radical mechanism. In turn, ddhCTP acts as a chain terminator for the RNA-dependent RNA polymerases from multiple viruses and directly inhibits viral replication. Therefore, inhibits a wide range of DNA and RNA viruses, including human cytomegalovirus (HCMV, hepatitis C virus (HCV, west Nile virus (WNV, dengue virus, sindbis virus, influenza A virus, sendai virus, vesicular stomatitis virus (VSV, zika virus, and human immunodeficiency virus (HIV-1. Promotes also TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs by facilitating 'Lys-63'-linked ubiquitination of IRAK1 by TRAF6. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor (TCR-mediated GATA3 activation and optimal T-helper 2 (Th2 cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins.,RSAD2,2510004L01Rik,cig33,cig5,vig1,Immunology & Inflammation,RSAD2
- Poids moléculaire
- 42kDa
- ID gène
- 91543
- UniProt
- Q8WXG1
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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