RASAL1 anticorps (AA 120-340)
Aperçu rapide pour RASAL1 anticorps (AA 120-340) (ABIN7269873)
Antigène
Voir toutes RASAL1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 120-340
-
Fonction
- RASAL1 Rabbit pAb
-
Séquence
- ICLSVQMLED GQGRCLRCHV LQARDLAPRD ISGTSDPFAR VFWGSQSLET STIKKTRFPH WDEVLELREM PGAPSPLRVE LWDWDMVGKN DFLGMVEFSP KTLQQKPPKG WFRLLPFPRA EEDSGGNLGA LRVKVRLIED RVLPSQCYQP LMELLMESVQ GPAEEDTASP LALLEELTLG DCRQDLATKL VKLFLGRGLA GRFLDYLTRR EVARTMDPNT L
-
Réactivité croisée
- Humain, Souris, Rat
-
Attributs du produit
- Polyclonal Antibodies
-
Purification
- Affinity purification
-
Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 120-340 of human RASAL1 (NP_004649.2).
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB,1:500 - 1:2000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))
-
Autre désignation
- RASAL1
-
Sujet
- The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described,RASAL1,RASAL,Cancer,Tumor suppressors,Signal Transduction,G protein signaling,Signal Transduction,RASAL1
-
Poids moléculaire
- 86kDa/90kDa
-
ID gène
- 8437
-
UniProt
- O95294
Antigène
-