Ras-Related C3 Botulinum Toxin Substrate 1 (RAC3A) (pSer71) anticorps

N° du produit ABIN7269877

Cet anticorps Lapin Monoclonal détecte spécifiquement Ras-Related C3 Botulinum Toxin Substrate 1 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Ras-Related C3 Botulinum Toxin Substrate 1 (RAC3A) (pSer71) anticorps (ABIN7269877)

Antigène: Ras-Related C3 Botulinum Toxin Substrate 1 (RAC3A)

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Application: Western Blotting (WB)

Détail du produit

Épitope: pSer71

Fonction: Phospho-Rac1/Cdc42-S71 Rabbit mAb

Réactivité croisée: Humain

Attributs du produit: Phosphorylated Antibodies

Purification: Affinity purification

Immunogène: A phospho specific peptide corresponding to residues surrounding S71 of human Rac1/Cdc42

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détail du antigène

Antigène: Ras-Related C3 Botulinum Toxin Substrate 1 (RAC3A)

Autre désignation: CDC42/RAC1

Sujet: The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013],CDC42Hs, G25K, TKS,CDC42/RAC1

Poids moléculaire: 24kDa

ID gène: 998, 5879

UniProt: P60953, P63000