Recombinant fusion protein containing a sequence corresponding to amino acids 230-360 of human RCCD1 (NP_001017919.1).
Isotype
IgG
Indications d'application
WB,1:500 - 1:2000
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Antigène
RCCD1
(RCC1 Domain Containing 1 (RCCD1))
Autre désignation
RCCD1
Sujet
Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8. Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation. Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT, potentially through the inhibition of KDM8.,RCCD1,Cell Biology & Developmental Biology,RCCD1