RNF170 anticorps (AA 46-120)
Aperçu rapide pour RNF170 anticorps (AA 46-120) (ABIN7270064)
Antigène
Voir toutes RNF170 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 46-120
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Fonction
- RNF170 Rabbit pAb
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Séquence
- RNVHQNIHPE NQELVRVLRE QLQTEQDAPA ATRQQFYTDM YCPICLHQAS FPVETNCGHL FCGACIIAYW RYGSW
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Réactivité croisée
- Souris
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 46-120 of human RNF170 (NP_001153696.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- RNF170 (Ring Finger Protein 170 (RNF170))
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Autre désignation
- RNF170
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Sujet
- This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene.,RNF170,ADSA,SNAX1,Cell Biology & Developmental Biology,RNF170
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Poids moléculaire
- 13kDa/18kDa/20kDa/22kDa/26kDa/29kDa
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ID gène
- 81790
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UniProt
- Q96K19
Antigène
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