This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Antigène
RNF20
(Ring Finger Protein 20 (RNF20))
Autre désignation
RNF20
Sujet
The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012],BRE1, BRE1A, hBRE1,Cell Biology & Developmental Biology,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_Ubiquitination,Epigenetics & Nuclear Signaling,Histones,Ubiquitin,RNF20