SCARB2 anticorps

N° du produit ABIN7270157

L’anticorps anti-SCARB2 Monoclonal Lapin est utilisé pour la détection de SCARB2 dans des échantillons de Humain. Il a été validé pour WB et IHC.

Aperçu rapide pour SCARB2 anticorps (ABIN7270157)

Antigène: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp SCARB2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SCARB2 anticorps

Fonction: SR-B2/LIMPII Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human SR-B2/SR-B2/LIMPII

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SCARB2

Antigène: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Autre désignation: SCARB2

Sujet: The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011],AMRF, CD36L2, EPM4, HLGP85, LGP85, LIMP-2, LIMPII, SR-BII,Cancer,Cardiovascular,Endocrine & Metabolism,Lipid Metabolism,Lipid Metabolism_Cholesterol Metabolism,Lipids,Signal Transduction,SCARB2

Poids moléculaire: 77kDa

ID gène: 950

UniProt: Q14108