SIM2 anticorps (AA 342-525)
Aperçu rapide pour SIM2 anticorps (AA 342-525) (ABIN7270320)
Antigène
Voir toutes SIM2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 342-525
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Fonction
- SIM2 Rabbit pAb
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Séquence
- LSLEQVSTAK SQDSWRTALS TSQETRKLVK PKNTKMKTKL RTNPYPPQQY SSFQMDKLEC GQLGNWRASP PASAAAPPEL QPHSESSDLL YTPSYSLPFS YHYGHFPLDS HVFSSKKPML PAKFGQPQGS PCEVARFFLS TLPASGECQW HYANPLVPSS SSPAKNPPEP PANTARHSLV PSYE
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Réactivité croisée
- Humain
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 342-525 of human SIM2 (NP_033664.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:100 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- SIM2 (Single-Minded Homolog 2 (SIM2))
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Autre désignation
- SIM2
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Sujet
- This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.,SIM2,HMC13F06,HMC29C01,SIM,bHLHe15,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor biomarkers,Neuroscience,SIM2
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Poids moléculaire
- 63kDa/73kDa
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ID gène
- 6493
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UniProt
- Q14190
Antigène
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