anticorps SNRB', anticorps SNRPB', anticorps Snrpn, anticorps zgc:77315, anticorps HCERN3, anticorps PWCR, anticorps RT-LI, anticorps SM-D, anticorps SMN, anticorps SNRNP-N, anticorps SNURF-SNRPN, anticorps sm-N, anticorps 2410045I01Rik, anticorps Peg4, anticorps Pwcr1, anticorps FE 294, anticorps FE 294 psi, anticorps FE294, anticorps FE294 psi, anticorps SNURF, anticorps SNRPN, anticorps QflA-11237, anticorps QtrA-10022, anticorps Sm-N, anticorps SmN, anticorps snRNP-N, anticorps small nuclear ribonucleoprotein polypeptide-like, anticorps small nuclear ribonucleoprotein polypeptides B and B1, anticorps small nuclear ribonucleoprotein polypeptide N, anticorps small nuclear ribonucleoprotein N, anticorps small nuclear ribonucleoparticle-associated protein (snRNP) mRNA, clone Sm51, anticorps SNRPN upstream reading frame, anticorps Small nuclear ribonucleoprotein-associated protein N, anticorps SNRPL, anticorps snrpb, anticorps SNRPN, anticorps Snrpn, anticorps snrpn, anticorps SNURF
Sujet
The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure.,SNRPN,HCERN3,PWCR,RT-LI,SM-D,SMN,SNRNP-N,SNURF-SNRPN,sm-N,PWS,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,SNRPN