SP1 anticorps (AA 420-620)
Aperçu rapide pour SP1 anticorps (AA 420-620) (ABIN7270506)
Antigène
Voir toutes SP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 420-620
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Fonction
- SP1 Rabbit pAb
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Séquence
- LSGQTFTTQA ISQETLQNLQ LQAVPNSGPI IIRTPTVGPN GQVSWQTLQL QNLQVQNPQA QTITLAPMQG VSLGQTSSSN TTLTPIASAA SIPAGTVTVN AAQLSSMPGL QTINLSALGT SGIQVHPIQG LPLAIANAPG DHGAQLGLHG AGGDGIHDDT AGGEEGENSP DAQPQAGRRT RREACTCPYC KDSEGRGSGD P
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 420-620 of human SP1 (NP_612482.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- SP1 (Sp1 Transcription Factor (SP1))
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Autre désignation
- SP1
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Sujet
- The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.,SP1,Epigenetics & Nuclear Signaling,Transcription Factors,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial Biogenesis,Nucleotide metabolism,Molecular processes,Neuroscience,Neurodegenerative Diseases,Stem Cells,SP1
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Poids moléculaire
- 75kDa/79kDa/80kDa
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ID gène
- 6667
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UniProt
- P08047
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Pathways
- Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
Antigène
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