SPTA1 anticorps

N° du produit ABIN7270517

L’anticorps Lapin Monoclonal anti-SPTA1 a été validé pour WB. Il convient pour détecter SPTA1 dans des échantillons de Humain.

Aperçu rapide pour SPTA1 anticorps (ABIN7270517)

Antigène: SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp SPTA1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SPTA1 anticorps

Fonction: alpha 1 Spectrin Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human alpha 1 Spectrin

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SPTA1

Antigène: SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

Autre désignation: SPTA1

Sujet: Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia. [provided by RefSeq, Jul 2008],EL2, HPP, HS3, SPH3, SPTA,Blood,Blood_Blood Cell Antigens,Cardiovascular,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Microfilaments,Signal Transduction,SPTA1

Poids moléculaire: 280kDa

ID gène: 6708

UniProt: P02549

Pathways: Regulation of Actin Filament Polymerization