SPIRE2 anticorps (AA 1-190)
Aperçu rapide pour SPIRE2 anticorps (AA 1-190) (ABIN7270538)
Antigène
Voir toutes SPIRE2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-190
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Fonction
- SPIRE2 Rabbit pAb
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Séquence
- MARAGSCGGA AAGAGRPEPW ELSLEEVLKA YEQPLNEEQA WAVCFQGCRG LRGSPGRRLR DTGDLLLRGD GSVGAREPEA AEPATMVVPL ASSEAQTVQS LGFAIYRALD WGLDESEERE LSPQLERLID LMANNDSEDS GCGAADEGYG GPEEEEEAEG VPRSVRTFAQ AMRLCAARLT DPRGAQAHYQ
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human SPIRE2 (NP_115827.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- SPIRE2 (Spire Homolog 2 (SPIRE2))
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Autre désignation
- SPIRE2
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Sujet
- Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport (By similarity. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis. Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly of nuclear actin filaments in response to DNA damage in order to facilitate movement of chromatin and repair factors after DNA damage.,SPIRE2,Spir-2,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,SPIRE2
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Poids moléculaire
- 65kDa/74kDa/79kDa
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ID gène
- 84501
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UniProt
- Q8WWL2
Antigène
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