anticorps TARDBP, anticorps TDP43, anticorps DKFZp459I2127, anticorps tardbp, anticorps ALS10, anticorps TDP-43, anticorps 1190002A23Rik, anticorps C85084, anticorps Tdp43, anticorps wu:fb77f02, anticorps wu:fc52g10, anticorps TAR DNA binding protein, anticorps Tardbp protein, anticorps TAR DNA binding protein L homeolog, anticorps TAR DNA-binding protein 43-like, anticorps TARDBP, anticorps tardbp, anticorps tardbp.L, anticorps Tardbp, anticorps LOC100621383
Sujet
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008],ALS10,TDP-43,TARDBP,TDP43,Apoptosis,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Neurodegenerative Diseases,Neurodegenerative Diseases Markers,Neurodegenerative Diseases_Amyotrophic lateral sclerosis,ALS,Neuroscience,Other Neurological disorders,RNA Binding,TARDBP