TBC1D5 anticorps (AA 446-795)

N° du produit ABIN7270750

Cet anticorps Lapin Polyclonal détecte spécifiquement TBC1D5 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour TBC1D5 anticorps (AA 446-795) (ABIN7270750)

Antigène: TBC1D5 (TBC1 Domain Family, Member 5 (TBC1D5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TBC1D5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TBC1D5 anticorps

Épitope: AA 446-795

Fonction: TBC1D5 Rabbit pAb

Séquence: NAKGAPLNIN KVSNSLINFG RKLISPAMAP GSAGGPVPGG NSSSSSSVVI PTRTSAEAPS HHLQQQQQQQ RLMKSESMPV QLNKGLSSKN ISSSPSVESL PGGREFTGSP PSSATKKDSF FSNISRSRSH SKTMGRKESE EELEAQISFL QGQLNDLDAM CKYCAKVMDT HLVNIQDVIL QENLEKEDQI LVSLAGLKQI KDILKGSLRF NQSQLEAEEN EQITIADNHY CSSGQGQGRG QGQSVQMSGA IKQASSETPG CTDRGNSDDF ILISKDDDGS SARGSFSGQA QPLRTLRSTS GKSQAPVCSP LVFSDPLMGP ASASSSNPSS SPDDDSSKDS GFTIVSPLDI

Réactivité croisée: Humain, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 446-795 of human TBC1D5 (NP_055559.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TBC1D5

Antigène: TBC1D5 (TBC1 Domain Family, Member 5 (TBC1D5))

Autre désignation: TBC1D5

Sujet: May act as a GTPase-activating protein (GAP for Rab family protein(s. May act as a GAP for RAB7A. Can displace RAB7A and retromer CSC subcomplex from the endosomal membrane to the cytosol, at least retromer displacement seems to require its catalytic activity. Required for retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN, the function seems to require its catalytic activity. Involved in regulation of autophagy. May act as a molecular switch between endosomal and autophagosomal transport and is involved in reprogramming vesicle trafficking upon autophagy induction. Involved in the trafficking of ATG9A upon activation of autophagy. May regulate the recruitment of ATG9A-AP2-containing vesicles to autophagic membranes.,TBC1D5,TBC1D5

Poids moléculaire: 89kDa/91kDa

ID gène: 9779

UniProt: Q92609