Thyroperoxidase anticorps

N° du produit ABIN7270865

L’anticorps anti-Thyroperoxidase Monoclonal Lapin est utilisé pour la détection de Thyroperoxidase dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour Thyroperoxidase anticorps (ABIN7270865)

Antigène: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Thyroperoxidase est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-Thyroperoxidase anticorps

Fonction: Thyroid Peroxidase Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human Thyroid Peroxidase

Isotype: IgG

Information d'application

Indications d'application: IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Thyroperoxidase

Antigène: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Autre désignation: TPO

Classe de substances: Viral Protein

Sujet: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011],MSA, TDH2A, TPX,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,Growth factors,Neuroscience,Signal Transduction,TPO

Poids moléculaire: 103kDa

ID gène: 7173

UniProt: P07202

Pathways: Thyroid Hormone Synthesis