TFE3 anticorps (AA 1-160)
Aperçu rapide pour TFE3 anticorps (AA 1-160) (ABIN7270893)
Antigène
Voir toutes TFE3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-160
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Fonction
- TFE3 Rabbit pAb
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Séquence
- MSHAAEPARD GVEASAEGPR AVFVLLEERR PADSAQLLSL NSLLPESGIV ADIELENVLD PDSFYELKSQ PLPLRSSLPI SLQATPATPA TLSASSSAGG SRTPAMSSSS SSRVLLRQQL MRAQAQEQER RERREQAAAA PFPSPAPASP AISVVGVSAG
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Réactivité croisée
- Humain
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human TFE3 (NP_006512.2).
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Isotype
- IgG
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Indications d'application
- IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- TFE3 (Transcription Factor E3 (TFE3))
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Autre désignation
- TFE3
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Sujet
- This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants.,TFE3,RCCP2,RCCX1,TFEA,bHLHe33,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Immunology & Inflammation,TFE3
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Poids moléculaire
- 11kDa/61kDa
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ID gène
- 7030
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UniProt
- P19532
Antigène
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