TADA3L anticorps (AA 270-369)

N° du produit ABIN7270900

Cet anticorps Lapin Polyclonal détecte spécifiquement TADA3L dans WB et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour TADA3L anticorps (AA 270-369) (ABIN7270900)

Antigène: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TADA3L est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-TADA3L anticorps

Épitope: AA 270-369

Fonction: TADA3 Rabbit pAb

Séquence: EENIISPMED SPIPDMSGKE SGADGASTSP RNQNKPFSVP HTKSLESRIK EELIAQGLLE SEDRPAEDSE DEVLAELRKR QAELKALSAH NRTKKHDLLR

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 270-369 of human TADA3 (NP_597814.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TADA3L

Antigène: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Autre désignation: TADA3

Sujet: DNA-binding transcriptional activator proteins increase the rate of transcription by interacting with the transcriptional machinery bound to the basal promoter in conjunction with adaptor proteins, possibly by acetylation and destabilization of nucleosomes. The protein encoded by this gene is a transcriptional activator adaptor and a component of the histone acetyl transferase (HAT) coactivator complex which plays a crucial role in chromatin modulation and cell cycle progression. Along with the other components of the complex, this protein links transcriptional activators bound to specific promoters, to histone acetylation and the transcriptional machinery. The protein is also involved in the stabilization and activation of the p53 tumor suppressor protein that plays a role in the cellular response to DNA damage. Alternate splicing results in multiple transcript variants of this gene.,TADA3,ADA3,NGG1,STAF54,TADA3L,hADA3,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Apoptosis,TADA3

Poids moléculaire: 41kDa/48kDa

ID gène: 10474

UniProt: O75528

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway