TGFB2 anticorps (AA 20-160)

N° du produit ABIN7270911

Cet anticorps anti-TGFB2 est un anticorps Lapin Polyclonal détectant TGFB2 dans WB et IHC. Adapté pour Humain.

Aperçu rapide pour TGFB2 anticorps (AA 20-160) (ABIN7270911)

Antigène: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TGFB2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-TGFB2 anticorps

Épitope: AA 20-160

Fonction: TGFB2 Rabbit pAb

Séquence: SLSTCSTLDM DQFMRKRIEA IRGQILSKLK LTSPPEDYPE PEEVPPEVIS IYNSTRDLLQ EKASRRAAAC ERERSDEEYY AKEVYKIDMP PFFPSETVCP VVTTPSGSVG SLCSRQSQVL CGYLDAIPPT FYRPYFRIVR F

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 20-160 of human TGFB2 (NP_001129071.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TGFB2

Antigène: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Autre désignation: TGFB2

Sujet: This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1,7)(q41,p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.,TGFB2,G-TSF,LDS4,TGF-beta2,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Growth factor,TGF-b-Smad Signaling Pathway,Wnt/β-Catenin Signaling Pathway,Endocrine & Metabolism,Stem Cells,Cardiovascular,Angiogenesis,Angiogenic growth factors,Ligand,TGFB2

Poids moléculaire: 47kDa/50kDa

ID gène: 7042

UniProt: P61812

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus