TMED10 anticorps (AA 35-190)
Aperçu rapide pour TMED10 anticorps (AA 35-190) (ABIN7270945)
Antigène
Voir toutes TMED10 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- AA 35-190
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Fonction
- [KO Validated] TMED10 Rabbit pAb
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Séquence
- HLPINSRKCL REEIHKDLLV TGAYEISDQS GGAGGLRSHL KITDSAGHIL YSKEDATKGK FAFTTEDYDM FEVCFESKGT GRIPDQLVIL DMKHGVEAKN YEEIAKVEKL KPLEVELRRL EDLSESIVND FAYMKKREEE MRDTNESTNT RVLYFS
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 35-190 of human TMED10 (NP_006818.3).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
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Autre désignation
- TMED10
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Sujet
- This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.,TMED10,P24(DELTA),S31I125,S31III125,TMP21,Tmp-21-I,p23,p24d1,Signal Transduction,Cell Biology & Developmental Biology,Hippo Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,TMED10
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Poids moléculaire
- 24kDa
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ID gène
- 10972
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UniProt
- P49755
Antigène
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