EZH1 anticorps (AA 471-510) (Cy5)

N° du produit ABIN717630

Cet anticorps anti-EZH1 est un anticorps Lapin Polyclonal détectant EZH1 dans WB, IF (cc) et IF (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour EZH1 anticorps (AA 471-510) (Cy5) (ABIN717630)

Antigène: EZH1 (Enhancer of Zeste Homolog 1 (EZH1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EZH1 est conjugé à/à la Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-EZH1 anticorps (Cy5)

Épitope: AA 471-510

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human EZH1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur EZH1

Antigène: EZH1 (Enhancer of Zeste Homolog 1 (EZH1))

Autre désignation: EZH1

Sujet:

Synonyms: Enhancer of zeste homolog 1Drosophila, Enhancer of zeste homolog 1, ENX-2, ENX2, EZH1, EZH1: enhancer of zeste homolog 1 Drosophila, EZH1_HUMAN, Histone-lysine N-methyltransferase EZH1, KIAA0388.

Background: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH1-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. Sequence similarities Belongs to the histone-lysine methyltransferase family. EZ subfamily.Contains 1 SET domain.

ID gène: 2145