ZIC2 anticorps (AA 1-220)

N° du produit ABIN7271432

L’anticorps Lapin Polyclonal anti-ZIC2 a été validé pour WB. Il convient pour détecter ZIC2 dans des échantillons de Humain.

Aperçu rapide pour ZIC2 anticorps (AA 1-220) (ABIN7271432)

Antigène: ZIC2

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZIC2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ZIC2 anticorps

Épitope: AA 1-220

Fonction: ZIC2 Rabbit pAb

Séquence: MLLDAGPQFP AIGVGSFARH HHHSAAAAAA AAAEMQDREL SLAAAQNGFV DSAAAHMGAF KLNPGAHELS PGQSSAFTSQ GPGAYPGSAA AAAAAAALGP HAAHVGSYSG PPFNSTRDFL FRSRGFGDSA PGGGQHGLFG PGAGGLHHAH SDAQGHLLFP GLPEQHGPHG SQNVLNGQMR LGLPGEVFGR SEQYRQVASP RTDPYSAAQL HNQYGPMNMN

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ZIC2 (NP_009060.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ZIC2

Antigène: ZIC2

Autre désignation: ZIC2

Sujet: This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Expansion of an alanine repeat in the C-terminus of the encoded protein and other mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.,ZIC2,HPE5,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Neuroscience,ZIC2

Poids moléculaire: 55kDa

ID gène: 7546

UniProt: O95409

Pathways: Tube Formation