ZNF451 anticorps (AA 600-900)

N° du produit ABIN7271489

L’anticorps Lapin Polyclonal anti-ZNF451 a été validé pour WB et IHC. Il convient pour détecter ZNF451 dans des échantillons de Humain.

Aperçu rapide pour ZNF451 anticorps (AA 600-900) (ABIN7271489)

Antigène: ZNF451 (Zinc Finger Protein 451 (ZNF451))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNF451 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ZNF451 anticorps

Épitope: AA 600-900

Fonction: ZNF451 Rabbit pAb

Séquence: SSPRGKWQCR ICEDMFDSQE YVKQHCMSLA SHKFHRYSCA HCRKPFHKIE TLYRHCQDEH DNEIKIKYFC GLCDLIFNVE EAFLSHYEEH HSIDYVFVSE KTETSIKTED DFPVIETSNQ LTCGCRESYI CKVNRKEDYS RCLQIMLDKG KLWFRCSLCS ATAQNLTDMN THIHQVHKEK SDEEEQQYVI KCGTCTKAFH DPESAQQHFH RKHCFLQKPS VAHFGSEKSN LYKFTASASH TERKLKQAIN YSKSLDMEKG VENDLSYQNI EEEIVELPDL DYLRTMTHIV FVDFDNWSNF F

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 600-900 of human ZNF451 (NP_001026794.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ZNF451

Antigène: ZNF451 (Zinc Finger Protein 451 (ZNF451))

Autre désignation: ZNF451

Sujet: E3 SUMO-protein ligase, has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins. Plays a role in protein SUMO2 modification in response to stress caused by DNA damage and by proteasome inhibitors (in vitro. Required for MCM4 sumoylation (By similarity. Has no activity with SUMO1. Preferentially transfers an additional SUMO2 chain onto the SUMO2 consensus site 'Lys-11'. Negatively regulates transcriptional activation mediated by the SMAD4 complex in response to TGF-beta signaling. Inhibits EP300-mediated acetylation of histone H3 at 'Lys-9'. Plays a role in regulating the transcription of AR targets.,ZNF451,COASTER,dJ417I1.1,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Nuclear hormone receptors,Signal Transduction,ZNF451

Poids moléculaire: 63kDa/115kDa/121kDa

ID gène: 26036

UniProt: Q9Y4E5