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Recombinant SARS-CoV-2 Spike anticorps (RBD)

Cet anticorps anti-SARS-CoV-2 Spike est un anticorps Souris Monoclonal détectant SARS-CoV-2 Spike dans . Adapté pour SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta et SARS CoV-2 Gamma.
N° du produit ABIN7271751

Aperçu rapide pour Recombinant SARS-CoV-2 Spike anticorps (RBD) (ABIN7271751)

Antigène

Voir toutes SARS-CoV-2 Spike Anticorps
SARS-CoV-2 Spike

Type d'anticorp

Recombinant Antibody

Reactivité

  • 88
  • 7
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta, SARS CoV-2 Gamma

Hôte

  • 32
  • 30
  • 21
  • 3
  • 2
  • 2
  • 1
  • 1
Souris

Clonalité

  • 60
  • 18
  • 11
Monoclonal

Conjugué

  • 76
  • 8
  • 3
  • 1
  • 1
Cet anticorp SARS-CoV-2 Spike est non-conjugé

Application

Veuillez nous consulter SVP

Classe de qualité

MALS verified

Clone

AM334
  • Épitope

    • 51
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    RBD

    Fonction

    Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (AM334) (Beta & Gamma Specific) (MALS verified)

    Specificité

    This product is a specific antibody against SARS-CoV-2 Spike protein RBD domain. No cross-reactivity is detected with Spike protein RBD domain of other coronaviruses, including SARS-CoV, MERS-CoV, HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1.

    Attributs du produit

    Recombinant Antibodies produced in HEK293. Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (Beta & Gamma Specific) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike RBD protein. The antibody is specific against the Beta (B.1.351) and Gamma (P.1) variant of SARS-CoV-2, and has no binding with the spike RBD of the wild type virus, the Alpha (B.1.1.7) variant, the Delta (B.1.617.2) variant and the Omicron (B.1.1.529, BA.2) variant.

    Immunogène

    Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (Beta & Gamma Specific) (ABIN7271751 and ABIN7273339) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike RBD protein. The antibody is specific against the Beta (B.1.351) and Gamma (P.1) variant of SARS-CoV-2, and has no binding with the spike RBD of the wild type virus, the Alpha (B.1.1.7) variant, the Delta (B.1.617.2) variant and the Omicron (B.1.1.529, BA.2) variant.

    Isotype

    IgG1
  • Restrictions

    For Research Use only
  • Format

    Liquid

    Stock

    -80 °C

    Stockage commentaire

    -70°C
  • Antigène

    SARS-CoV-2 Spike

    Sujet

    It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
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