CD1a anticorps

N° du produit ABIN7271833

Cet anticorps Souris Monoclonal détecte spécifiquement CD1a dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour CD1a anticorps (ABIN7271833)

Antigène: CD1a

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD1a est non-conjugé

Application: Flow Cytometry (FACS)

Classe de qualité: GMP Grade

Clone: OKT6

Détail du produit anti-CD1a anticorps

Fonction: CD1a Unconjugated Antibody

Attributs du produit: The clone OKT6, a mouse monoclonal antibody selectively recognizes 49- kDa type I transmembrane glycoprotein non-covalently associated with β2-microglobulin known as CD1a. The CD1a glycoprotein has structural similarities to MHC class I molecule and plays important role in antigen-presenting mechanism to T-cell receptors present on NK T-cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation NK T-cells, CD1a has been implicated in thymic T cell development. CD1a has been used as a marker for DCs in a range of human tumors and the density of CD1a DC has been associated with clinical outcome in patients with lung, colon, gastric, nasopharyngeal, laryngeal and tongue carcinomas.

Purification: Purified

Pureté: >95 %

Immunogène: Human acute lymphoblastic leukemia cells

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur CD1a

Antigène: CD1a

Autre désignation: CD1a

ID gène: 909

UniProt: P06126

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process