SARS-CoV-2 NSP1 anticorps

N° du produit ABIN7272996

L’anticorps anti-SARS-CoV-2 NSP1 Polyclonal Chèvre est utilisé pour la détection de SARS-CoV-2 NSP1 dans des échantillons de SARS Coronavirus-2 (SARS-CoV-2). Il a été validé pour WB.

Aperçu rapide pour SARS-CoV-2 NSP1 anticorps (ABIN7272996)

Antigène: SARS-CoV-2 NSP1 (SARS-CoV-2 Host Translation Inhibitor Nsp1 (SARS-CoV-2 NSP1))

Reactivité: SARS Coronavirus-2 (SARS-CoV-2)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp SARS-CoV-2 NSP1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SARS-CoV-2 NSP1 anticorps

Fonction: anti-NSP1 (SARS-CoV-2)

Séquence: MESLVPGFNE KTHVQLSLPV LQVRDVLVRG FGDSVEEVLS EARQHLKDGT CGLVEVEKGV LPQLEQPYVF IKRSDARTAP HGHVMVELVA ELEGIQYGRS GETLGVLVPH VGEIPVAYRK VLLRKNGNKG AGGHSYGADL KSFDLGDELG TDPYEDFQEN WNTKHSSGVT RELMRELNGG

Specificité: In lysates of transfected cells with the plasmid containing the sequence used, detects the fusion protein by Western blot.

Réactivité croisée (Details): Reacts with SARS-CoV-2 protein

Purification: Epitope affinity purified

Immunogène: Affinity purified recombinant fusion protein Nsp1 of SARS-CoV-2 produced in E. coli.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:2,000

Restrictions: For Research Use only

Stockage

Concentration: 3 mg/mL

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: The antibody solution should be gently mixed before use.

Stock: 4 °C,-20 °C

Stockage commentaire: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Détails sur SARS-CoV-2 NSP1

Antigène: SARS-CoV-2 NSP1 (SARS-CoV-2 Host Translation Inhibitor Nsp1 (SARS-CoV-2 NSP1))

Autre désignation: NSP1 (SARS-CoV-2)

Classe de substances: Viral Protein

Sujet:

Host translation inhibitor Nsp1 is part of the multifunctional protein replicase polyprotein 1ab that is involved in the transcription and replication of viral RNA. NSP1 inhibits the host translation by interacting with the 40S ribosomal subunit. The nsp1-40S ribosome complex further induces an endonucleolytic cleavage near the 5'UTR of host mRNAs, targeting them for degradation. Therefore, Nsp1 facilitates efficient viral gene expression in infected cells and evasion from host immune response by suppressing host gene expression.

Host translation inhibitor, Nsp1 SARS Coronavirus-2 antibody.