PFN2 anticorps
Aperçu rapide pour PFN2 anticorps (ABIN7383994)
Antigène
Voir toutes PFN2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Purification
- Affinity purification
-
Immunogène
- Synthetic peptide of human PFN2
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB 1:500-1:2000, IHC 1:25-1:100
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 0.3 mg/mL
-
Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- PFN2 (Profilin 2 (PFN2))
-
Autre désignation
- PFN2
-
Sujet
- D3S1319E,PFL,PFN 2,Pfn2,PROF2,Profilin II,Profilin-2,Profilin2,ProfilinII,The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
-
Poids moléculaire
- 15 kDa
-
NCBI Accession
- NP_444252
-
UniProt
- P35080
-
Pathways
- Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
Antigène
-