Myoferlin anticorps
Aperçu rapide pour Myoferlin anticorps (ABIN7384124)
Antigène
Voir toutes Myoferlin (MYOF) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein of human MYOF (NP_038479.1).
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Isotype
- IgG
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Indications d'application
- WB 1:200-1:2000
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Myoferlin (MYOF)
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Autre désignation
- MYOF
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Sujet
- MYOF,FER1L3,myoferlin,Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.
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Poids moléculaire
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Observed_MW: 250 kDa
Calculated_MW: 17 kDa/46 kDa/49 kDa/179 kDa/229 kDa/233 kDa/234 kDa
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ID gène
- 26509
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UniProt
- Q9NZM1
Antigène
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