RAD21 anticorps

N° du produit ABIN7384393

Cet anticorps anti-RAD21 est un anticorps Lapin Monoclonal détectant RAD21 dans WB et IHC (p). Adapté pour Humain et Hamster.

Aperçu rapide pour RAD21 anticorps (ABIN7384393)

Antigène: RAD21 (RAD21 Homolog (RAD21))

Reactivité: Humain, Hamster

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp RAD21 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: R03-5I0

Détail du produit anti-RAD21 anticorps

Purification: Affinity Purified

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000 IHC 1:50-1:100

Restrictions: For Research Use only

Stockage

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RAD21

Antigène: RAD21 (RAD21 Homolog (RAD21))

Autre désignation: Rad21

Sujet: MGS,HR21,MCD1,NXP1,SCC1,CDLS4,hHR21,HRAD21,RAD21, also named as Nuclear matrix protein 1, is a 631 amino acid protein, which belongs to the rad21 family. The calculated molecular weight of RAD21 is 72 kDa, but the phosphorylated RAD21 is about 120 kDa. The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells

Poids moléculaire:

Observed_MW: 130kDa

Calculated_MW: 72kDa

ID gène: 5885

UniProt: O60216

Pathways: Positive Regulation of Endopeptidase Activity