YTHDF1 anticorps

N° du produit ABIN7384402

Cet anticorps anti-YTHDF1 est un anticorps Lapin Monoclonal détectant YTHDF1 dans WB. Adapté pour Humain et Hamster.

Aperçu rapide pour YTHDF1 anticorps (ABIN7384402)

Antigène: YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))

Reactivité: Humain, Hamster

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp YTHDF1 est non-conjugé

Application: Western Blotting (WB)

Clone: R05-2E7

Détail du produit anti-YTHDF1 anticorps

Purification: Affinity Purified

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-1:2000

Restrictions: For Research Use only

Stockage

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur YTHDF1

Antigène: YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))

Autre désignation: YTHDF1

Sujet: C20orf21,DF1,YTHDF1, also named as YTH domain-containing family protein 1 or C20orf21, is a 559 amino acid protein, which localizes in the cytoplasm. YTHDF1 specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. YTHDF1 acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation. YTHDF1 exists two isoform and calculated molecular weight of isoforms are 61 kDa and 21 kDa.

Poids moléculaire:

Observed_MW: 61kDa

Calculated_MW: 61kDa

ID gène: 54915

UniProt: P59326