YTHDF1 anticorps

N° du produit ABIN7384402

Détail du produit anti-YTHDF1 anticorps

Antigène: YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))

Reactivité: Humain, Hamster

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp YTHDF1 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity Purified

Clone: R05-2E7

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-1:2000

Restrictions: For Research Use only

Stockage

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur YTHDF1

Antigène: YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))

Autre désignation: YTHDF1 (YTHDF1 Produits)

Synonymes: anticorps fb49c02, anticorps zgc:55657, anticorps wu:fb49c02, anticorps wu:fi19h06, anticorps wu:fj87f09, anticorps wu:fp06c11, anticorps MGC75606, anticorps MGC68505, anticorps 2210410K23Rik, anticorps 8030473O16, anticorps C20orf21, anticorps YTH N(6)-methyladenosine RNA binding protein 1, anticorps YTH N(6)-methyladenosine RNA binding protein 1 L homeolog, anticorps YTH N6-methyladenosine RNA binding protein 1, anticorps YTH domain family 1, anticorps ythdf1, anticorps ythdf1.L, anticorps YTHDF1, anticorps Ythdf1

Sujet: C20orf21,DF1,YTHDF1, also named as YTH domain-containing family protein 1 or C20orf21, is a 559 amino acid protein, which localizes in the cytoplasm. YTHDF1 specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. YTHDF1 acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation. YTHDF1 exists two isoform and calculated molecular weight of isoforms are 61 kDa and 21 kDa.

Poids moléculaire:

Observed_MW: 61kDa

Calculated_MW: 61kDa

ID gène: 54915

UniProt: P59326