Integrin beta 5 anticorps
Aperçu rapide pour Integrin beta 5 anticorps (ABIN7384459)
Antigène
Voir toutes Integrin beta 5 (ITGB5) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- Affinity Purified
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:1000
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Restrictions
- For Research Use only
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Concentration
- 300 μg/mL
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Buffer
- 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Integrin beta 5 (ITGB5)
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Autre désignation
- Integrin beta 5
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Sujet
- FLJ26658,Integrin beta-5,Integrin subunit beta 5,integrin,beta 5,ITB5,Itgb5,Testis secretory sperm-binding protein Li 217p,Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors, both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors.
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Poids moléculaire
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Observed_MW: 88kDa
Calculated_MW: 88kDa
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ID gène
- 3693
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UniProt
- P18084
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Pathways
- Integrin Complex
Antigène
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