STING/TMEM173 anticorps

N° du produit ABIN7384500

L’anticorps Lapin Monoclonal anti-STING/TMEM173 a été validé pour WB et IHC (p). Il convient pour détecter STING/TMEM173 dans des échantillons de Humain et Rat.

Aperçu rapide pour STING/TMEM173 anticorps (ABIN7384500)

Antigène: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp STING/TMEM173 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: R06-9A7

Détail du produit anti-STING/TMEM173 anticorps

Purification: Affinity Purified

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000 IHC 1:50-1:100

Restrictions: For Research Use only

Stockage

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur STING/TMEM173

Antigène: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Autre désignation: Transmembrane Protein 173

Sujet: Endoplasmic reticulum IFN stimulator,Endoplasmic reticulum interferon stimulator,ERIS,FLJ38577,hMITA,hSTING,Mediator of IRF3 activation,MITA,Mitochondrial mediator of IRF3 activation,MPYS,N terminal methionine proline tyrosine serine plasma membrane tetraspanner,NET23,Stimulator of interferon genes,Stimulator of interferon genes protein,STING,TM173,Tmem173,Transmembrane protein 173,This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Poids moléculaire:

Observed_MW: 40kDa

Calculated_MW: 42kDa

ID gène: 340061

UniProt: Q86WV6

Pathways: Activation of Innate immune Response