STING/TMEM173 anticorps
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- Antigène Voir toutes STING/TMEM173 (TMEM173) Anticorps
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
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Reactivité
- Humain, Rat
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp STING/TMEM173 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Affinity Purified
- Clone
- R06-9A7
- Isotype
- IgG
- Top Product
- Discover our top product TMEM173 Anticorps primaire
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- Indications d'application
- WB 1:500-1:1000 IHC 1:50-1:100
- Restrictions
- For Research Use only
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- Concentration
- 300 μg/mL
- Buffer
- 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
- Autre désignation
- Transmembrane Protein 173 (TMEM173 Produits)
- Synonymes
- anticorps ERIS, anticorps MITA, anticorps MPYS, anticorps NET23, anticorps STING, anticorps 2610307O08Rik, anticorps Mita, anticorps RGD1562552, anticorps transmembrane protein 173, anticorps TMEM173, anticorps Tmem173
- Sujet
- Endoplasmic reticulum IFN stimulator,Endoplasmic reticulum interferon stimulator,ERIS,FLJ38577,hMITA,hSTING,Mediator of IRF3 activation,MITA,Mitochondrial mediator of IRF3 activation,MPYS,N terminal methionine proline tyrosine serine plasma membrane tetraspanner,NET23,Stimulator of interferon genes,Stimulator of interferon genes protein,STING,TM173,Tmem173,Transmembrane protein 173,This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
- Poids moléculaire
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Observed_MW: 40kDa
Calculated_MW: 42kDa
- ID gène
- 340061
- UniProt
- Q86WV6
- Pathways
- Activation of Innate immune Response
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