K63-Linked Polyubiquitin anticorps

N° du produit ABIN7384503

L’anticorps anti-K63-Linked Polyubiquitin Monoclonal Lapin est utilisé pour la détection de K63-Linked Polyubiquitin dans des échantillons de Humain. Il a été validé pour WB, IF et IHC (p).

Aperçu rapide pour K63-Linked Polyubiquitin anticorps (ABIN7384503)

Antigène: K63-Linked Polyubiquitin

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: R06-2H7

Détail du produit

Purification: Affinity Purified

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000 IHC 1:50-1:100 IF 1:50-1:100

Restrictions: For Research Use only

Stockage

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détail du antigène

Antigène: K63-Linked Polyubiquitin

Autre désignation: Ubiquitin K63

Sujet: UBB,UBB,Ubiquitin,This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. 

Poids moléculaire:

Observed_MW: 8kDa

Calculated_MW: 8kDa

ID gène: 7314

UniProt: P0CG47