Cet anticorps Mammalian Cells Monoclonal détecte spécifiquement IL5 (Mepolizumab Biosimilar) dans ELISA. Il présente une réactivité avec des échantillons de Humain.
Research Grade
Reactivité: Humain
Hôte: Humanized
Chimeric
unconjugated
Recombinant Antibody
Restrictions
For Research Use only
Buffer
PBS pH 7.5
Stock
-80 °C
Stockage commentaire
store at -80°C
Antigène
IL5 (Mepolizumab Biosimilar)
Classe de substances
Biosimilar
Sujet
SB-240563 Mepolizumab is a fully humanized recombinant IgG1 kappa monoclonal antibody directed against IL-5 produced in Chinese hamster ovary cells. (EGPA) and eosinophilia syndrome (HES). The pathogenesis of eosinophils is complex, but IL-5 is considered a key eosinophilic factor, involved in the differentiation, recruitment, activation and prolonged survival of eosinophils in peripheral tissues. Activated eosinophils further stimulate the inflammatory response, and also induce tissue damage and promote fibrosis, all of which contribute to the multifactorial symptoms of eosinophilic disease. Mepolizumab is used to treat severe asthma.