FLCN anticorps (AA 1-50)

N° du produit ABIN7448434

Cet anticorps Lapin Polyclonal détecte spécifiquement FLCN dans IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour FLCN anticorps (AA 1-50) (ABIN7448434)

Antigène: FLCN (Folliculin (FLCN))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FLCN est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-FLCN anticorps

Épitope: AA 1-50

Fonction: Rabbit anti-BHD IHC Antibody, Affinity Purified

Homologie: Gorilla,Chimpanzee

Purification: Affinity Purified

Immunogène: Between AA 1 and 50

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur FLCN

Antigène: FLCN (Folliculin (FLCN))

Autre désignation: BHD

Classe de substances: Amino Acid

Sujet: Background: Defects in the folliculin (FLCN) gene are the cause of Birt-Hogg-Dube syndrome (BHD) [MIM:135150]. BHD is a rare autosomal dominant genodermatosis characterized by hair follicle hamartomas (fibrofolliculomas), kidney tumors, and spontaneous pneumothorax. Fibrofolliculomas are part of the triad of BHD skin lesions that also includes trichodiscomas and acrochordons. Defects in FLCN may also be the cause of primary spontaneous pneumothorax (PSP) [MIM:173600], a condition in which air is present in the pleural space in the absence of a precipitating event, such as trauma or lung disease. Folliculin may be a tumor suppressor involved in colorectal and renal cell tumorigenesis [taken from the Universal Protein Resource (UniProt) Q8NFG4].

ID gène: 201163

NCBI Accession: NP_659434

UniProt: Q8NFG4

Pathways: Cell-Cell Junction Organization