XPO1 anticorps (C-Term)

N° du produit ABIN7448488

Cet anticorps Lapin Polyclonal détecte spécifiquement XPO1 dans IHC. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour XPO1 anticorps (C-Term) (ABIN7448488)

Antigène: XPO1 (Exportin 1 (XPO1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XPO1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-XPO1 anticorps

Épitope: C-Term

Fonction: Rabbit anti-CRM1 IHC Antibody, Affinity Purified

Homologie: Orangutan,Monkey,Gorilla,Chimpanzee,Northern white-cheeked gibbon,Crab-eating macaque,White-tufted-ear marmoset

Purification: Affinity Purified

Immunogène: Between AA 1025 and C-term

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur XPO1

Antigène: XPO1 (Exportin 1 (XPO1))

Autre désignation: CRM1

Sujet: Background: Chromosome region maintenance 1 protein homolog (CRM1) is the Ran-GTP-binding nuclear export receptor for proteins bearing a leucine rich nuclear export signal and RNAs. CRM1 also possesses a mitotic function as it localizes to kinetochores, and with Ran-GTP, recruits Ran-GTPase-activating protein (Ran-GAP1) and Ran-binding protein (Ran-BP2) for proper mitotic spindle assembly and chromosome segregation. Additionally, CRM1 is suggested to function as a loading dock of various cell cycle and checkpoint factors such as cyclins, Cdks, p53 and BRCA1, to regulate proper chromosome duplication and genomic stability.

ID gène: 7514

NCBI Accession: NP_003391

UniProt: O14980

Pathways: M Phase